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Doxepine-paroxetine

102 bytes removed, 20 February
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* '''Before day 0:''' gradually reduce dosage of doxepin to a maximum of 100 mg/day.* '''Day 1:''' reduce dosage of doxepin to 50 mg/day.* '''Day 8:''' reduce dosage of doxepin to 25 mg/day.* '''Day 15:''' stop administration of doxepin.{{TCAdecrease25p3d}}
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* '''Day 15:7 and after''' : At approximately 50-25% of the original TCA dose start administration paroxetine at 50% of the target dose.* '''Day 14:''' Increase paroxetine in a normal dosage to 100% of 20 mg/day.the target dose 
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* {{theorSS}}Safe target dose paroxetine = 20 mg* Paroxetine paroxetine is a strong CYP2D6 inhibitor of CYP2D6, which metabolizes metabolize doxepin. }}
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