Open main menu

Psychiatrienet β

Changes

Duloxetine-paroxetine

260 bytes removed, 20 February
no edit summary
| to = paroxetine
| stop =
* '''Before day 0:''' gradually reduce dosage of duloxetine to a maximum of 60 mg/ day.* '''Day 1:''' reduce a dosage of 60 mg/day to 30 mg/day.* '''Day 8:''' | stop duloxetine.= {{StopSSRI,SNRI}}| start = * '''Day 8:''' start paroxetine the next day in a normal dosage of 20 mg/day.{{StartAntidepressant}}
| info =
* Paroxetine and duloxetine slow each others metabolism by CYP2D6-inhibition.* {{theorSS}}Safe target dose paroxetine = 20 mg
}}