* '''Day 3:''' reduce dosage of imipramine to 25 mg/day.
| start =
Caution is necessary.
* '''Day 1:''' simultaneously start administration of mianserine in a low dosage of 30 mg/day.
* '''Day 8:''' stop administration of imipramine and continue administration of mianserine.
* If necessary, increase dosage of mianserine. }}