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| to = mianserine
| stop =
* '''Before day 01:''' gradually reduce dosage of imipramine to a maximum of 75 mg/day.
* '''Day 1:''' reduce dosage of imipramine to 50 mg/day.
* '''Day 3:''' reduce dosage of imipramine to 25 mg/day.
| start =
* '''Day 1:''' simultaneously start administration of mianserine in a low dosage of 30 mg/day.
* '''Day 8:''' stop administration of imipramine and continue administration of mianserine.
* If necessary, increase dosage of mianserine. }}