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| to = clomipramine
| stop =
* '''Day 0Before day 1:''' gradually reduce dosage of mianserine to a maximum of 60 mg/ day.
* '''Day 1:''' reduce a dosage of 60 mg/day to 30 mg/day.
| start =
No wash-out period is needed.
* '''Day 1:''' simultaneously start administration of clomipramine in a dosage of 50 mg/day.
* '''Day 8:''' stop administration of mianserine and continue administration of clomipramine in a dosage of 75 mg/day. * If necessary, increase the dosage of clomipramine.
* Start low, go slow.}}
