Difference between revisions of "Combining-Ziprasidone-Risperidone"
From Psychiatrienet
(Created page with '{{Drugcombi | base = ziprasidone | add = risperidone | info = | start = * Stop ziprasidone before starting risperidone. | cave = * The concurrent use of ziprasidone with other...') |
|||
| (One intermediate revision by one other user not shown) | |||
| Line 4: | Line 4: | ||
| info = | | info = | ||
| start = | | start = | ||
| − | + | {{IrrationalCombiAP}} | |
| cave = | | cave = | ||
* The concurrent use of ziprasidone with other medications that can prolong the QT interval is considered contraindicated.<ref> {{Drugscominteract|risperidone-with-ziprasidone-2019-0-2330-0|risperidone|ziprasidone}}</ref> | * The concurrent use of ziprasidone with other medications that can prolong the QT interval is considered contraindicated.<ref> {{Drugscominteract|risperidone-with-ziprasidone-2019-0-2330-0|risperidone|ziprasidone}}</ref> | ||
}} | }} | ||
Latest revision as of 09:52, 25 June 2010
| ||||||||||||||||||||||||||||||||||||||||||
| ||||||||||||||||||||||||||||||||||||||||||
Adding risperidone to ziprasidone.
General information- Ziprasidone is metabolized by CYP1A2 (minor) and CYP3A4.
- Risperidone is principally metabolized by CYP2D6 to an active metabolite 9-OH-risperidone (paliperidone).
Start risperidone- The combination of these 2 antipsychotics seems to be irrational from a pharmacotherapeutical point of view.
Cave- The concurrent use of ziprasidone with other medications that can prolong the QT interval is considered contraindicated.[4]
- ↑ 1.0 1.1 KNMP; Informatorium Medicamentorum 2023; Monografie "risperidon" (Dutch)
- ↑ Woods SW; Chlorpromazine equivalent doses for the newer atypical antipsychotics J Clin Psychiatry 2003;64:663-667
- ↑ 3.0 3.1 The Lundbeck Institute; Psychotropics; Terminal Plasma Half-lives
- ↑ Interactions between risperidone and ziprasidone on drugs.com
The editors of psychiatrienet.nl take the greatest care to provide up-to-date and accurate information on this site. Nevertheless, mistakes and omissions cannot be entirely excluded. No rights devolve from the information provided. The editors and other providers of information to this site accept no responsibility for the content of this site or for the information provided therein; neither do they accept responsibility for possible damages which may derive from the use of the information on this site or from the linked sites. The editorial board accepts no responsibility for the content of the (linked) sites, for access to them, or for the products and services on these sites, nor for the occurrence of errors, viruses, and/or disruptions in service.
