Difference between revisions of "Template:Switch-to-(9OH-)risperidone"

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* Test text
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''There are 2 switch possibities'':
* Day 1: Switch to oral risperidone or oral paliperidone: see this switch in the main cross table.
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* Day 1-29: Maintain on oral risperidone or oral paliperidone and examine the effects.
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'''Number 1 (the general approach):'''
* Day 30: stop oral risperidone or oral paliperidone and administer paliperidone-LA.''
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* '''Day 1:''' Switch to oral risperidone (or oral paliperidone): see this switch in the main cross table.
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* '''Day 1-29:''' Maintain on oral risperidone (or oral paliperidone) and examine the effects.
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* '''Day 30:''' stop oral risperidone (or oral paliperidone) and administer paliperidone-LA: see this switch in the main cross table.
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Oral risperidone has better and more stable bioavailability properties than has oral 9-OH-risperidone=paliperidone. Food increases the absorption with 50-60% of the latter.
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'''Number 2 (if a patient in the past reacted well on risperidon or paliperidone=9-OH-risperidone):'''

Latest revision as of 15:57, 16 May 2011

There are 2 switch possibities:

Number 1 (the general approach):

  • Day 1: Switch to oral risperidone (or oral paliperidone): see this switch in the main cross table.
  • Day 1-29: Maintain on oral risperidone (or oral paliperidone) and examine the effects.
  • Day 30: stop oral risperidone (or oral paliperidone) and administer paliperidone-LA: see this switch in the main cross table.

Oral risperidone has better and more stable bioavailability properties than has oral 9-OH-risperidone=paliperidone. Food increases the absorption with 50-60% of the latter.


Number 2 (if a patient in the past reacted well on risperidon or paliperidone=9-OH-risperidone):