[[File{{Drugswitch | from = Vortioxetine | to = agomelatine | stop = {{downVenla}}| start = * '''Day 7:Example''' simultaneously start administration of agomelatine in a dosage of 25 mg/day.jpg]][[File* '''Day 15:Empty''' continue administration of agomelatine.jpg]]If necessary, increase dosage of agomelatine to 50 mg/day.<ref name="agoswitch"> {{Pubmed|20196187|McAllister-Williams RH et al. The use of antidepressants in clinical practice: focus on agomelatine. Hum Psychopharmacol. 2010 Mar 1;25(2):95-102}}</ref>}}