| to = trazodone
| stop =
* Gradually reduce dosage of bupropion to a maximum of 150 mg/day. * When a dosage of 150 mg/day is reached, stop administration.{{stopBupropion}}
| start =
{{Inc25p3d2}}* Start trazodone the same day in a normal dosage of 100-150 mg/day.
| info =
* Bupropion and its metabolites have long elimination times, so plasma concentrations will reduce gradually.
* Bupropion and its metabolites slow the metabolism of trazodone by CYP2D6.
{{review}}
}}