Difference between revisions of "Bupropion-venlafaxine"
From Psychiatrienet
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| − | * '''Day 1 | + | | start = |
| − | * '''Day 8:''' | + | * ''' Day 1: ''' Start venlafaxine with a dosage of 37,5 mg/day. |
| + | * ''' Day 8: ''' increase dosage of venlafaxine to a dosage of 75 mg/day. | ||
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| − | + | * Bupropion slows the metabolism of venlafaxine by CYP2D6. | |
| − | * Bupropion slows the metabolism of venlafaxine by CYP2D6. | ||
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Latest revision as of 11:45, 4 August 2023
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Switch medication from bupropion to venlafaxine.[1] [2]
Stop bupropion - Day 1: Stop bupropion.
- bupropion can be stopped abruptly for every dosage.[3]
Start venlafaxine- Day 1: Start venlafaxine with a dosage of 37,5 mg/day.
- Day 8: increase dosage of venlafaxine to a dosage of 75 mg/day.
More information- Bupropion slows the metabolism of venlafaxine by CYP2D6.
- ↑ Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
- ↑ Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
- ↑ Multidisciplinair document Afbouwen Overige Antidepressiva 2023
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