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Difference between revisions of "Venlafaxine-paroxetine"

 
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| to = paroxetine
 
| to = paroxetine
 
| stop =  
 
| stop =  
* Gradually reduce dosage of venlafaxine to a maximum of 75 mg/day.
+
{{stopVenlafaxine}}
* When a dosage of 75 mg/day is reached, stop administration.
 
 
| start =  
 
| start =  
 
* No wash-out period is needed.  
 
* No wash-out period is needed.  
* Start paroxetine the next day in a normal dosage of 20 mg/day.
+
* ''' Day 9: ''' start paroxetine in a normal dosage of 20 mg/day.
 
 
 
}}
 
}}

Latest revision as of 13:19, 4 November 2015

Venlafaxine
Type Antidepressant
Group SNRI
links
Medscape Venlafaxine
PubChem 5656
PubMed Venlafaxine
Kompas (Dutch) Venlafaxine
Wikipedia Venlafaxine
paroxetine
Type Antidepressant
Group SSRI
links
Medscape paroxetine
PubChem 43815
PubMed paroxetine
Kompas (Dutch) paroxetine
Wikipedia paroxetine

Switch medication from venlafaxine to paroxetine.[1] [2]

Nietinrijdenbord.png Stop venlafaxine
  • Before day 1: gradually reduce dosage of venlafaxine to a maximum of 75 mg/ day.
  • Day 1: reduce a dosage of 75 mg/day to 37,5 mg/day.
  • Day 8: stop administration of venlafaxine.
Eenrichtingbord.png Start paroxetine
  • No wash-out period is needed.
  • Day 9: start paroxetine in a normal dosage of 20 mg/day.


  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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