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Difference between revisions of "Escitalopram-tranylcypromine"

 
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{{Drugswitch  
 
{{Drugswitch  
| from = escitalopram
+
| from = Escitalopram
 
| to = tranylcypromine
 
| to = tranylcypromine
| stop = {{StopEscitalopram}}
+
| stop =  
 +
{{generaldecrease25p3d}}
 +
{{7dWashout}}
 +
 
 
| start =  
 
| start =  
* '''Day 8-21:''' a wash-out period of two weeks is necessary.
+
*a wash-out period of 7 days is necessary.
* '''Day 22:''' Start administration of tranylcypromine in low dosage of 20 mg/day for one week.
+
{{Starttranyl}}
* '''Day 29:''' after this week the dosage of tranylcypromine can be increased if necessary.
 
 
| caveat =  
 
| caveat =  
* Occurrence of serotonin syndrome is reported when a wash-out period (of two weeks) is not considered.
+
{{caveSS}}
 
}}
 
}}

Latest revision as of 12:28, 8 March 2024

Escitalopram
Type Antidepressant
Group SSRI
links
Medscape Escitalopram
PubChem 10832572
PubMed Escitalopram
Kompas (Dutch) Escitalopram
Wikipedia Escitalopram
Tranylcypromine
Type Antidepressant
Group MAO-I
links
Medscape Tranylcypromine
PubChem 5530
PubMed Tranylcypromine
Kompas (Dutch) Tranylcypromine
Wikipedia Tranylcypromine

Switch medication from Escitalopram to tranylcypromine.[1] [2]

Nietinrijdenbord.png Stop Escitalopram
  • Decrease with about 25% of original dose every 3 days
  • Stop and wait 7 days for washout
Eenrichtingbord.png Start tranylcypromine
  • a wash-out period of 7 days is necessary.
  • Start tranylcypromine in a low dosage of 20 mg/day for one week.
  • After this week the dosage of tranylcypromine can be increased.
Letopbord.png Cave


  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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