Difference between revisions of "Template:SwitchMAO"

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*Tranylcypromine and fenelzine are irreversible MAO inhibitors for MAO-A and MAO-B. Fenelzine has higher affinity for MAO-A, whereas tranylcypromine has higher affinity for MAO-B. Side effects could occur during a switch. Known side effect for tranylcypromine are sleeping problems, agitation and orthostatic hypotension. Known side effects in fenelzine are oedema and/or increased liver enzyme levels. In addition, monitoring of sodium levels is adviced.<ref>A van Diepen et al. De lange mars van farma naar patiënt Medisch Contact May 2021</ref>
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*Tranylcypromine and fenelzine are irreversible MAO inhibitors for MAO-A and MAO-B. Fenelzine has higher affinity for MAO-A, whereas tranylcypromine has higher affinity for MAO-B. Side effects could occur during a switch. In addition, monitoring of sodium levels is adviced.<ref>A van Diepen et al. De lange mars van farma naar patiënt Medisch Contact May 2021</ref>
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*Known side effect for tranylcypromine are sleeping problems, agitation and orthostatic hypotension.  
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*Known side effects in fenelzine are oedema and/or increased liver enzyme levels.
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* It is adviced to admit the patient in a mental health care clinic for intensive monitoring during this switch.<ref>van den Eynde et al. Richtlijn voor het gebruik van klassieke MAO-remmers Psyfar 2023 nr 2</ref>

Latest revision as of 16:25, 14 April 2026

  • Tranylcypromine and fenelzine are irreversible MAO inhibitors for MAO-A and MAO-B. Fenelzine has higher affinity for MAO-A, whereas tranylcypromine has higher affinity for MAO-B. Side effects could occur during a switch. In addition, monitoring of sodium levels is adviced.[1]
  • Known side effect for tranylcypromine are sleeping problems, agitation and orthostatic hypotension.
  • Known side effects in fenelzine are oedema and/or increased liver enzyme levels.
  • It is adviced to admit the patient in a mental health care clinic for intensive monitoring during this switch.[2]
  • A van Diepen et al. De lange mars van farma naar patiënt Medisch Contact May 2021
  • van den Eynde et al. Richtlijn voor het gebruik van klassieke MAO-remmers Psyfar 2023 nr 2