Difference between revisions of "Bupropion-citalopram"

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(Created page with '{{Drugswitch | from = bupropion | to = citalopram | stop = * Gradually reduce dosage of bupropion to a maximum of 150 mg/ day. * When a dosage of 150 mg/day is reached, stop...')
 
 
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| to = citalopram  
 
| to = citalopram  
 
| stop =  
 
| stop =  
* Gradually reduce dosage of bupropion to a maximum of 150 mg/ day.
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{{stopBupropion}}
* When a dosage of 150 mg/day is reached, stop administration.
 
 
| start =  
 
| start =  
* No wash-out period is needed.
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* ''' Day 1: ''' Start citalopram with a dosage of 10 mg/day.
* Start citalopram/escitalopram the next day in normal dosage of 20 mg/day citalopram or 10 mg/day escitalopram.
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* ''' Day 4: ''' If necessary, gradually increase dosage
 
| info =   
 
| info =   
* Bupropion and its metabolites have long elimination times, so plasma concentrations will reduce gradually.}}
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Latest revision as of 11:05, 4 August 2023

Bupropion
Type Antidepressant
Group other
links
ATC-code N06AX12
Medscape Bupropion
PubChem 444
PubMed Bupropion
Kompas (Dutch) Bupropion
Wikipedia Bupropion
Citalopram
Type Antidepressant
Group SSRI
links
ATC-code N06AB04
Medscape Citalopram
PubChem 2771
PubMed Citalopram
Kompas (Dutch) citalopram
Wikipedia citalopram

Switch medication from bupropion to citalopram.[1] [2]

Nietinrijdenbord.png Stop bupropion
  • Day 1: Stop bupropion.
  • bupropion can be stopped abruptly for every dosage.[3]
Eenrichtingbord.png Start citalopram
  • Day 1: Start citalopram with a dosage of 10 mg/day.
  • Day 4: If necessary, gradually increase dosage


  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
  3. Multidisciplinair document Afbouwen Overige Antidepressiva 2023
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