Difference between revisions of "Vortioxetine-tranylcypromine"
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| − | + | {{Drugswitch | |
| + | | from = vortioxetine | ||
| + | | to = tranylcypromine | ||
| + | | stop = | ||
| + | * '''Day 1:''' Stop vortioxetine. | ||
| + | * vortioxetine can be stopped abruptly for every dosage.<ref>Multidisciplinair document Afbouwen Overige Antidepressiva 2023</ref> | ||
| + | {{14dwashout}} | ||
| + | | start = | ||
| + | * a wash-out period of two weeks is necessary. | ||
| + | {{Starttranyl}} | ||
| + | | caveat = | ||
| + | {{caveSS}} | ||
| + | }} | ||
Latest revision as of 14:40, 8 March 2024
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Switch medication from vortioxetine to tranylcypromine.[1] [2]
Stop vortioxetine - Day 1: Stop vortioxetine.
- vortioxetine can be stopped abruptly for every dosage.[3]
- Stop and wait 14 days for washout
Start tranylcypromine- a wash-out period of two weeks is necessary.
- Start tranylcypromine in a low dosage of 20 mg/day for one week.
- After this week the dosage of tranylcypromine can be increased.
Cave- Occurrence of the serotonin syndrome is possible without wash-out period.
- ↑ Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
- ↑ Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
- ↑ Multidisciplinair document Afbouwen Overige Antidepressiva 2023
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