Difference between revisions of "Vortioxetine-agomelatine"
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{{Drugswitch | {{Drugswitch | ||
| − | | from = | + | | from = vortioxetine |
| to = agomelatine | | to = agomelatine | ||
| stop = | | stop = | ||
| − | | | + | {{Stopvortioxetine}} |
| − | + | | start = {{StartAgomelatine|15}} | |
| − | + | ||
| − | | | + | |info = * References <ref name="vortiswitch"> {{Pubmed|24570588 |Katona et al. New generation multi-modal antidepressants: focus on vortioxetine for major depressive disorder. 2014 2014 Feb 19;10:349-54}}</ref> <ref name="informatorium">{{KNMP|vortioxetine}}</ref> <ref name="Summary of Product Characteristics"> [http://www.ema.europa.eu/docs/en_GB/document_library/EPAR_-_Product_Information/human/002717/WC500159449.pdf Summary of Product Characteristics Vortioxetine]</ref> |
| − | * | + | |
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}} | }} | ||
Latest revision as of 12:14, 4 August 2023
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Switch medication from vortioxetine to agomelatine.[1] [2]
Stop vortioxetine 
Start agomelatine- Day 1: simultaneously start administration of agomelatine in a dosage of 25 mg/day.[5]
- If necessary, increase dosage of agomelatine to 50 mg/day.
More information- ↑ Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
- ↑ Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
- ↑ CBG meb, accessed june 2023, SmPC Vortioxetine
- ↑ Multidisciplinair document Afbouwen Overige Antidepressiva 2023
- ↑ McAllister-Williams RH et al. The use of antidepressants in clinical practice: focus on agomelatine. Hum Psychopharmacol. 2010 Mar 1;25(2):95-102
- ↑ Katona et al. New generation multi-modal antidepressants: focus on vortioxetine for major depressive disorder. 2014 2014 Feb 19;10:349-54
- ↑ KNMP; Informatorium Medicamentorum 2023; Monografie "vortioxetine" (Dutch)
- ↑ Summary of Product Characteristics Vortioxetine
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