Difference between revisions of "Haloperidol-Lurasidone"
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Switch medication from Haloperidol to Lurasidone.[5] [6]
Stop Haloperidol - Day 1-4: approx. 75% of initial dose
- Day 5-8: approx. 50% of initial dose
- Day 9-12: approx. 25% of initial dose
- Day 13: stop
Start Lurasidone- Day 1-4: approx. 25% of target dose
- Day 5-8: approx. 50% of target dose
- Day 9-12: approx. 75% of target dose
- Day 13: target dose
More information- More information on switching to lurasidon: see reference. [7]
— Haloperidol — Lurasidone
- ↑ WHO Collaborating Centre for Drug Statistics Methodology ATC=N05AD01
- ↑ 2.0 2.1 2.2 KNMP; Informatorium Medicamentorum 2023; Monografie "haloperidol" (Dutch)
- ↑ 3.0 3.1 The Lundbeck Institute; Psychotropics; Terminal Plasma Half-lives
- ↑ 4.0 4.1 Farmacotherapeutisch Kompas; Inleidende Tekst Antipsychotica (dutch)
- ↑ Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
- ↑ Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
- ↑ McEvoy JP et al. Effectiveness of lurasidone in patients with schizophrenia or schizoaffective disorder switched from other antipsychotics: a randomized, 6-week, open-label study.J Clin Psychiatry. 2013 Feb;74(2):170-9.
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