Difference between revisions of "Fluvoxamine-mirtazapine"

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| from = fluvoxamine  
 
| from = fluvoxamine  
 
| to = mirtazapine  
 
| to = mirtazapine  
| stop =  
+
| stop = {{StopSSRI,SNRI}}
* '''Before day 0:''' gradually reduce dosage of fluvoxamine to a maximum of 50 mg/ day, when this dosage is > 50 mg/day.
+
| start = {{StartAntidepressant}}
* '''Day 1:''' reduce fluvoxamine to a dosage of 25 mg/day.
+
| info =
| start =
+
* Safe target dose mirtazapine = 15 mg
* '''Day 1:''' simultaneously start administration of mirtazapine in a low dosage of 15 mg/day for one week.
+
}}
* '''Day 8:''' stop administration of fluvoxamine and continue administration of just mirtazapine. If necessary increase dosage of mirtazapine to normal (30 mg/day).}}
 

Latest revision as of 16:53, 24 February 2023

Fluvoxamine
Type Antidepressant
Group SSRI
links
Medscape Fluvoxamine
PubChem 5324346
PubMed Fluvoxamine
Kompas (Dutch) Fluvoxamine
Wikipedia Fluvoxamine
Mirtazapine
Type Antidepressant
Group other
links
Medscape Mirtazapine
PubChem 4205
PubMed Mirtazapine
Kompas (Dutch) Mirtazapine
Wikipedia Mirtazapine

Switch medication from fluvoxamine to mirtazapine.[1] [2]

Nietinrijdenbord.png Stop fluvoxamine
  • Day 1: Decrease dose to 50%
  • Day 8: Stop
Eenrichtingbord.png Start mirtazapine
  • Day 1: Start with 50% of the target dose
  • Day 8: Increase dose to 100% of the target dose
  • Day 9 and after: Gradually increase dose as necessary
Infobord.png More information
  • Safe target dose mirtazapine = 15 mg
  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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