Difference between revisions of "Mirtazapine-trazodone"
From Psychiatrienet
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* '''Day 8:''' stop administration of mirtazapine. | * '''Day 8:''' stop administration of mirtazapine. | ||
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| − | * Start administration of trazodone | + | * '''Day 9:'''Start administration of trazodone in a dosage of 100-150 mg/day |
| − | * If necessary, increase dosage of trazodone | + | * If necessary, increase dosage of trazodone.}} |
Revision as of 15:28, 10 July 2009
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Switch medication from mirtazapine to trazodone.[1] [2]
Stop mirtazapine - Before day 0: gradually reduce the dosage of mirtazapine to a maximum of 30 mg/day.
- Day 1: reduce dosage of mirtazapine to 15 mg/day.
- Day 8: stop administration of mirtazapine.
Start trazodone- Day 9:Start administration of trazodone in a dosage of 100-150 mg/day
- If necessary, increase dosage of trazodone.
- ↑ Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
- ↑ Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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