Difference between revisions of "Combining-Gabapentin-Aripiprazole"
From Psychiatrienet
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{{Drugcombi | {{Drugcombi | ||
| base = gabapentin | | base = gabapentin | ||
− | | add = aripiprazole | + | | add = aripiprazole |
− | | info = | + | | info = |
− | |||
− | |||
| start = | | start = | ||
− | * Start | + | * Start aripiprazol according to the general dosing advice. |
| cave = | | cave = | ||
* Central nervous system- and/or respiratory-depressant effects may be additively or synergistically increased in patients taking multiple drugs that cause these effects. <ref name="drugscom"> | * Central nervous system- and/or respiratory-depressant effects may be additively or synergistically increased in patients taking multiple drugs that cause these effects. <ref name="drugscom"> | ||
{{Drugscominteract|aripiprazole-with-gabapentin-233-0-1147-0|aripiprazole|gabapentin}}</ref> | {{Drugscominteract|aripiprazole-with-gabapentin-233-0-1147-0|aripiprazole|gabapentin}}</ref> | ||
}} | }} |
Revision as of 10:31, 18 June 2010
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Adding aripiprazole to gabapentin.
- Gabapentin is eliminated unchanged by the kidney for 100%.
- Aripiprazole is metabolized by CYP2D6 and CYP3A4 to an active metabolite.
- Start aripiprazol according to the general dosing advice.
- Central nervous system- and/or respiratory-depressant effects may be additively or synergistically increased in patients taking multiple drugs that cause these effects. [2]
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