Difference between revisions of "Escitalopram-mirtazapine"
From Psychiatrienet
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| stop = {{StopEscitalopram}} | | stop = {{StopEscitalopram}} | ||
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| − | * '''Day 1:''' simultaneously start mirtazapine in a normal dosage of 15 | + | * '''Day 1:''' simultaneously start mirtazapine in a normal dosage of 15 mg/day. |
| − | * '''Day 8:''' | + | * '''Day 8:''' if necessary gradually increase mirtazapine dosage to 30-45 mg/day |
| − | | info = {{ | + | |
| + | | info = {{SSRI14d}} | ||
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Revision as of 12:46, 21 October 2015
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Switch medication from escitalopram to mirtazapine.[1] [2]
Stop escitalopram - Before day 1: gradually reduce dosage of escitalopram to a maximum of 10 mg/day, when this dosage is >10 mg/day.
- Day 1: reduce dosage of escitalopram to a maximum of 5 mg/day.
- Day 8: stop administration of escitalopram.
Start mirtazapine- Day 1: simultaneously start mirtazapine in a normal dosage of 15 mg/day.
- Day 8: if necessary gradually increase mirtazapine dosage to 30-45 mg/day
More information- The reduction of the SSRI doses in 7-14 days could cause emotional instability, headache and flu-like symptoms. One could extend this period.
- ↑ Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
- ↑ Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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