Difference between revisions of "Fluvoxamine-mianserine"
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| − | * '''Before day | + | * '''Before day 1:''' gradually reduce dosage of fluvoxamine to a maximum of 50 mg/ day, when this dosage is > 50 mg/day. |
* '''Day 1:''' reduce fluvoxamine to a dosage of 25 mg/day. | * '''Day 1:''' reduce fluvoxamine to a dosage of 25 mg/day. | ||
| start = | | start = | ||
* '''Day 1:''' simultaneously start administration of mianserine in a low dosage of 30 mg/day for one week. | * '''Day 1:''' simultaneously start administration of mianserine in a low dosage of 30 mg/day for one week. | ||
* '''Day 8:''' stop administration of fluvoxamine and continue administration of mianserine only. If necessary increase dosage of mianserine to normal (60 mg/day).}} | * '''Day 8:''' stop administration of fluvoxamine and continue administration of mianserine only. If necessary increase dosage of mianserine to normal (60 mg/day).}} | ||
Latest revision as of 11:21, 17 November 2009
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Switch medication from fluvoxamine to mianserine.[1] [2]
Stop fluvoxamine - Before day 1: gradually reduce dosage of fluvoxamine to a maximum of 50 mg/ day, when this dosage is > 50 mg/day.
- Day 1: reduce fluvoxamine to a dosage of 25 mg/day.
Start mianserine- Day 1: simultaneously start administration of mianserine in a low dosage of 30 mg/day for one week.
- Day 8: stop administration of fluvoxamine and continue administration of mianserine only. If necessary increase dosage of mianserine to normal (60 mg/day).
- ↑ Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
- ↑ Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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