Difference between revisions of "Fluoxetine-hypericum"

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| to = hypericum  
 
| to = hypericum  
 
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* '''Before day 0:''' gradually reduce dosage of fluoxetine to a maximum of 20 mg/day, when this dosage is > 20 mg/day.  
+
* Gradually reduce dosage of fluoxetine to a maximum of 20 mg/day, when this dosage is > 20 mg/day.  
* '''Day 1:''' stop administration of fluoxetine.
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* When a dosage of 20 mg/day is reached, stop administration of fluoxetine.
 
| start =  
 
| start =  
 
Caution is necessary.
 
Caution is necessary.

Revision as of 12:03, 7 May 2009

Fluoxetine
Type Antidepressant
Group SSRI
links
Medscape Fluoxetine
PubChem 3386
PubMed Fluoxetine
Kompas (Dutch) Fluoxetine
Wikipedia Fluoxetine
Hypericum
Type Antidepressant
Group other
links
EMEA 10130408en
PubMed Hypericum
Kompas (Dutch) hypericum extract
Wikipedia St John's wort

Switch medication from fluoxetine to hypericum.[1] [2]

Nietinrijdenbord.png Stop fluoxetine
  • Gradually reduce dosage of fluoxetine to a maximum of 20 mg/day, when this dosage is > 20 mg/day.
  • When a dosage of 20 mg/day is reached, stop administration of fluoxetine.
Eenrichtingbord.png Start hypericum

Caution is necessary.

  • Day 1-28: a wash-out period of four weeks is necessary.
  • Day 29: start administration of hypericum in a dosage of 300 mg three times a day (900 mg/day).
Infobord.png More information
  • Occurrence of serotonin syndrome is theoretically possible, so caution is necessary.
  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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