Difference between revisions of "Dosulepine-venlafaxine"
From Psychiatrienet
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* '''Day 7:''' stop administration of dosulepine. | * '''Day 7:''' stop administration of dosulepine. | ||
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| − | * '''Day 8:''' | + | * '''Day 8:''' {{startVenla}} |
| info = | | info = | ||
* Occurrence of serotonin syndrome is theoretically possible, so caution is necessary.}} | * Occurrence of serotonin syndrome is theoretically possible, so caution is necessary.}} | ||
Revision as of 08:02, 20 July 2009
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Switch medication from dosulepine to venlafaxine.[1] [2]
Stop dosulepine - Before day 0: gradually reduce dosage of dosulepine to a maximum of 75 mg/day.
- Day 1: reduce dosage of dosulepine to 50 mg/day.
- Day 3: reduce dosage of dosulepine to 25 mg/day.
- Day 7: stop administration of dosulepine.
Start venlafaxine- Day 8: Start administration of venlafaxine in a normal dosage of 37,5 mg or 75 mg (slow release) /day.
More information- Occurrence of serotonin syndrome is theoretically possible, so caution is necessary.
- ↑ Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
- ↑ Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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