Difference between revisions of "Vortioxetine-citalopram"
From Psychiatrienet
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* No wash-out period is needed. | * No wash-out period is needed. | ||
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| info = | | info = | ||
* {{theorSS}}<ref>[http://www.ema.europa.eu/docs/nl_NL/document_library/EPAR_-_Product_Information/human/002717/WC500159449.pdf European Medicines Agency. SmPC Brintellix 5 mg.]</ref> | * {{theorSS}}<ref>[http://www.ema.europa.eu/docs/nl_NL/document_library/EPAR_-_Product_Information/human/002717/WC500159449.pdf European Medicines Agency. SmPC Brintellix 5 mg.]</ref> | ||
}} | }} | ||
Revision as of 16:53, 11 March 2015
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Switch medication from vortioxetine to citalopram.[1] [2]
Stop vortioxetine - Day 1: reduce dosage of vortioxetine to 5 mg/day.
- Day 7: stop administration of vortioxetine.
Start citalopram- No wash-out period is needed.
- Day 8:'Start citalopram in a normal dosage of 20 mg/day.
More information- Occurrence of the serotonin syndrome is not likely, but theoretically possible, so caution is necessary.[3]
- ↑ Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
- ↑ Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
- ↑ European Medicines Agency. SmPC Brintellix 5 mg.
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