Difference between revisions of "Amitriptyline-tranylcypromine"
From Psychiatrienet
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| start = | | start = | ||
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Revision as of 12:18, 20 June 2016
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Switch medication from amitriptyline to tranylcypromine.[1] [2]
Stop amitriptyline - Day 1: Decrease with about 25% of the original dose per 3 days.
- Stop and wait 14 days for washout
Start tranylcypromine- Start at the first day after the washout period with about 25% of target dose.
Cave- Occurrence of the serotonin syndrome is possible without wash-out period.
- ↑ Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
- ↑ Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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