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Bupropion-sertraline

Revision as of 08:17, 14 October 2015 by Anoek (talk | contribs)
Bupropion
Type Antidepressant
Group other
links
ATC-code N06AX12
Medscape Bupropion
PubChem 444
PubMed Bupropion
Kompas (Dutch) Bupropion
Wikipedia Bupropion
Sertraline
Type Antidepressant
Group SSRI
links
Medscape Sertraline
PubChem 68617
PubMed Sertraline
Kompas (Dutch) Sertraline
Wikipedia Sertraline

Switch medication from bupropion to sertraline.[1] [2]

Nietinrijdenbord.png Stop bupropion
  • Before day 1: Gradually reduce dosage of bupropion to a maximum of 150 mg/ day.
  • Day 1: Stop administration of bupropion
Eenrichtingbord.png Start sertraline
  • Day 2: Start sertraline in the dosage of 25 mg/day.
  • After 3 weeks: If necessary increase dosage gradually to 50-200 mg/day
Infobord.png More information
  • No wash-out period is needed.
  • Bupropion and its metabolites have long elimination times, so plasma concentrations will reduce gradually.
  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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