Haloperidol LA-Sertindole

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Haloperidol
long acting
Type Antipsychotic
Group Butyrophenones
links
ATC-code N05AD01
Medscape Haloperidol
PubChem 3559
PubMed Haloperidol
Drugs.com haloperidol
Kompas (Dutch) Haloperidol
Wikipedia Haloperidol
Sertindole
Type Antipsychotic
Group Atypical AP
links
PubChem 60149
PubMed Sertindole
Kompas (Dutch) Sertindole
Wikipedia Sertindole

Switch medication from Haloperidol_LA to Sertindole.[4] [5]

Nietinrijdenbord.png Stop Haloperidol_LA
  • Day 1: Last depot injection
Eenrichtingbord.png Start Sertindole
  • Week 1-3: approx. 25% of target dose
  • Week 4-6: approx. 50% of target dose
  • Week 7-9: approx. 75% of target dose
  • Week 10: target dose
Letopbord.png Cave
  • During this switch ECG monitoring is required because of possible QT-interval prolongation[6][7]
Infobord.png More information
Empty.jpg
Nietinrijdenbord.png — Haloperidol_LA
Eenrichtingbord.png — Sertindole


  1. WHO Collaborating Centre for Drug Statistics Methodology ATC=N05AD01
  2. 2.0 2.1 The Lundbeck Institute; Psychotropics; Terminal Plasma Half-lives
  3. 3.0 3.1 Farmacotherapeutisch Kompas; Inleidende Tekst Antipsychotica (dutch)
  4. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  5. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
  6. SPC Sertindole (Dutch)
  7. SPC Sertindole
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