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Fluvoxamine-mianserine

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Fluvoxamine
Type Antidepressant
Group SSRI
links
Medscape Fluvoxamine
PubChem 5324346
PubMed Fluvoxamine
Kompas (Dutch) Fluvoxamine
Wikipedia Fluvoxamine
Mianserine
Type Antidepressant
Group other
links
PubChem 4184
PubMed Mianserine
Kompas (Dutch) Mianserine
Wikipedia Mianserine

Switch medication from fluvoxamine to mianserine.[1] [2]

Nietinrijdenbord.png Stop fluvoxamine
  • Before day 0: gradually reduce dosage of fluvoxamine to a maximum of 50 mg/ day, when this dosage is > 50 mg/day.
  • Day 1: reduce fluvoxamine to a dosage of 25 mg/day.
Eenrichtingbord.png Start mianserine
  • Day 1: simultaneously start administration of mianserine in a low dosage of 30 mg/day for one week.
  • Day 8: stop administration of fluvoxamine and continue administration of mianserine only. If necessary increase dosage of mianserine to normal (60 mg/day).


  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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