Switch medication from trazodone to agomelatine.[1]
[2]
Stop trazodone
- Day 1: Decrease with about 25% of the original dose per 3 days.
Start agomelatine
- Day 1: simultaneously start administration of agomelatine in a dosage of 25 mg/day.[3]
- If necessary, increase dosage of agomelatine to 50 mg/day.
More information
- The content of trazodone in the tablet, for example 100 mg or 150 mg, determines which exact doses are given.
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Stop trazodone 
Start agomelatine
More information