Switch medication from bupropion to tranylcypromine.[1]
[2]
Stop bupropion
- Day 1: Stop bupropion.
- bupropion can be stopped abruptly for every dosage.[3]
Start tranylcypromine
- Day 1: start and increase the dose with about 25% of the target dose every 3 days.
More information
- No wash-out period is necessary
- ↑ Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
- ↑ Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
- ↑ Multidisciplinair document Afbouwen Overige Antidepressiva 2023
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Stop bupropion 
Start tranylcypromine
More information