Switch medication from nortriptyline to tranylcypromine.[1]
[2]
Stop nortriptyline
- Day 1: Decrease with about 25% of the original dose per 3 days.
Start tranylcypromine
- Start tranylcypromine in a low dosage of 20 mg/day for one week.
- After this week the dosage of tranylcypromine can be increased.
More information
- No wash-out period is necessary[3]
- ↑ Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
- ↑ Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
- ↑ KNMP; Informatorium Medicamentorum 2023; Monografie "{{{1}}}" (Dutch)
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Stop nortriptyline 
Start tranylcypromine
More information