* This switch is intended for paliperidone long acting (Xeplion®, 30 days)
{{Drugswitch | from = Paliperidone LA | to = Risperidone[1] | stop =
- Day 1: Last depot injection
| start = {{StartOral afterDepot} | info =
- During this switch you could monitor ECG, especially in patients prone to QT-conduction problems.
- There is a possibility of QT interval prolongation.[2]
- the T1/2 of a monthly paliperidon depot is approximately 25-49 days.[3]
}}
- ↑ A. Risselada, Switchen van en naar depotantipsychotica - een update; Psyfar, june 2022 nummer 2
- ↑ Stöllberger C, Huber JO, Finsterer J, Antipsychotic drugs and QT prolongation. Int Clin Psychopharmacol. 2005 Sep;20(5):243-51.
- ↑ KNMP Kennisbank, informatorium medicamentorum: Paliperidon