Haloperidol-Paliperidone LA

Haloperidol Type Antipsychotic Group Butyrophenones links ATC-code N05AD01 Medscape Haloperidol PubChem 3559 PubMed Haloperidol Drugs.com haloperidol Kompas (Dutch) Haloperidol Wikipedia Haloperidol more info DDD 8mg dose 0.25-15mg Cth 5μg/L Ctox 20μg/L EQ-dosage 1 haloperidol T1/2 17.5h bioavailability 60-70% administration O,IM,IV

Paliperidone long acting Type Antipsychotic Group Atypical AP links Medscape Paliperidone PubChem 23724979 PubMed Paliperidone Kompas (Dutch) Paliperidone Wikipedia Paliperidone more info

Switch medication from Haloperidol to Paliperidone_LA.

Stop Haloperidol

• Week 1-3: approx. 75% of initial dose
• Week 4-6: approx. 50% of initial dose
• Week 7-9: approx. 25% of initial dose
• Week 10: stop

Start Paliperidone_LA

• Day 1: Start depot according general dosing advice (Dotted line in graph)

More information

• Alternatively, first switch to oral form and then switch to depot to manage possible (adverse) reactions. With a direct switch to a depot it is advisable to administer a low testdose in order to exclude adverse reactions.
  

The editors of psychiatrienet.nl take the greatest care to provide up-to-date and accurate information on this site. Nevertheless, mistakes and omissions cannot be entirely excluded. No rights devolve from the information provided. The editors and other providers of information to this site accept no responsibility for the content of this site or for the information provided therein; neither do they accept responsibility for possible damages which may derive from the use of the information on this site or from the linked sites. The editorial board accepts no responsibility for the content of the (linked) sites, for access to them, or for the products and services on these sites, nor for the occurrence of errors, viruses, and/or disruptions in service.