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Sertraline-fluoxetine

Revision as of 20:29, 3 May 2009 by Alexandra (talk | contribs) (Created page with '{{Drugswitch | from = sertraline | to = fluoxetine | stop = * Gradually reduce dosage of sertraline to a maximum of 50 mg/ day, when this dosage is > 50 mg/day. * When a dosa...')
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Sertraline
Type Antidepressant
Group SSRI
links
Medscape Sertraline
PubChem 68617
PubMed Sertraline
Kompas (Dutch) Sertraline
Wikipedia Sertraline
Fluoxetine
Type Antidepressant
Group SSRI
links
Medscape Fluoxetine
PubChem 3386
PubMed Fluoxetine
Kompas (Dutch) Fluoxetine
Wikipedia Fluoxetine

Switch medication from sertraline to fluoxetine.[1] [2]

Nietinrijdenbord.png Stop sertraline
  • Gradually reduce dosage of sertraline to a maximum of 50 mg/ day, when this dosage is > 50 mg/day.
  • When a dosage of 50 mg/day is reached, stop administration.
Eenrichtingbord.png Start fluoxetine
  • No wash-out period is needed.
  • Start fluoxetine the next day in normal dosage of 20 mg/day.


  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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