Combining-Lamotrigine-Ziprasidone

Lamotrigine Type moodstabilizer Group anticonvulsant links ATC-code N03AX09 PubChem 3878 PubMed Lamotrigine Drugs.com lamotrigine Kompas (Dutch) Lamotrigine Wikipedia Lamotrigine more info DDD 300mg Cth 1500-15000μg/L Ctox 20000μg/L T1/2 33h bioavailability 98% administration O

Ziprasidone Type Antipsychotic Group Atypical AP Other use Moodstabilizer links Medscape Ziprasidone PubChem 60854 PubMed Ziprasidone Wikipedia Ziprasidone more info

Adding ziprasidone to lamotrigine.

General information

• Lamotrigine is principally metabolised by UDP-glucuronosyltransferases.
• Ziprasidone is metabolized by CYP1A2 (minor) and CYP3A4.

Start ziprasidone

• Start ziprasidone according to the general dosing advice.

Cave

• Central nervous system- and/or respiratory-depressant effects may be additively or synergistically increased in patients taking multiple drugs that cause these effects.

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