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Moclobemide-paroxetine

Revision as of 11:57, 4 May 2009 by Alexandra (talk | contribs) (Created page with '{{Drugswitch | from = moclobemide | to = paroxetine | stop = * Gradually reduce dosage of moclobemide to a maximum of 300 mg/ day. * When a dosage of 300 mg/day is reached, ...')
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Moclobemide
Type Antidepressant
Group MAO-I
links
Medscape Moclobemide
PubChem 4235
PubMed Moclobemide
Kompas (Dutch) Moclobemide
Wikipedia Moclobemide
paroxetine
Type Antidepressant
Group SSRI
links
Medscape paroxetine
PubChem 43815
PubMed paroxetine
Kompas (Dutch) paroxetine
Wikipedia paroxetine

Switch medication from moclobemide to paroxetine.[1] [2]

Nietinrijdenbord.png Stop moclobemide
  • Gradually reduce dosage of moclobemide to a maximum of 300 mg/ day.
  • When a dosage of 300 mg/day is reached, stop administration.
Eenrichtingbord.png Start paroxetine
  • Day 1-2: a wash-out period of two days is necessary.
  • Day 3: start paroxetine after this period in a normal dosage of 20 mg/day.


  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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