{{Drugswitch | from = fluoxetine | to = vortioxetine | stop =
- Before day 1: reduce dosage of fluoxetine to 20 mg/day, when this dosage is > 20 mg/day.
- Day 1: stop administration
| start =
- Day 1-21: A wash-out period is needed.
- Day 22: Start vortioxetine in a dosage of 10 mg/day.
- After day 28 : If necessary, increase gradually the dosage of vortioxetine.
| info =
- Fluoxetine slows the metabolism of vortioxetine via CYP2D6, so caution is necessary for at least four weeks after stopping fluoxetine.
- {{theorSS}
}}