{{Drugswitch | from = tranylcypromine | to = sertraline | stop =
- Gradually decrease the dosage of tranylcypromine with 10-20 mg/week.
- When a dosage of 10 mg/day is reached, stop administration.
| start =
- Day 1-14: a wash-out period of two weeks is necessary.
- Day 15: start sertralin after this period in a normal dosage of 50 mg/day.
| info =
- Occurrence of the serotonin syndrome is possible without a wash-out period.
- The wash-out period is necessary for the MAO enzymes to restore their function.
{{review]] }}