Switch medication from fluvoxamine to bupropion.[1]
[2]
Stop fluvoxamine
- Gradually reduce dosage of fluvoxamine to a maximum of 50 mg/ day, when this dosage is > 50 mg/day.
Start bupropion
- Day 1: reduce fluvoxamine to a dosage of 25 mg/day and start administration of bupropion in a normal dosage of 150 mg/day for one week.
- Day 8: stop administration of fluvoxamine and continue administration of just bupropion.
More information
- This switch is currently being reviewed.
- ↑ Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
- ↑ Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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Stop fluvoxamine 
Start bupropion
More information