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Switch medication from nortriptyline to vortioxetine.[1] [2]
Stop nortriptyline - Day 1: reduce dosage to 50%.
- Day 8: stop
Start vortioxetine- No wash-out period is needed.
- Day 9: start administration of vortioxetine in a normal dosage of 10 mg/day.
- ↑ Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
- ↑ Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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