Haloperidol-Aripiprazole

Haloperidol Type Antipsychotic Group Butyrophenones links ATC-code N05AD01 Medscape Haloperidol PubChem 3559 PubMed Haloperidol Drugs.com haloperidol Kompas (Dutch) Haloperidol Wikipedia Haloperidol more info DDD 8mg dose 0.25-15mg Cth 5μg/L Ctox 20μg/L EQ-dosage 1 haloperidol T1/2 17.5h bioavailability 60-70% administration O,IM,IV

Ariprazole Type Antipsychotic Group Atypical AP Other use moodstabilizer links EMEA abilify PubChem 60975 PubMed Ariprazole Kompas (Dutch) Ariprazole Wikipedia Ariprazole more info

Switch medication from Haloperidol to Aripiprazole.

Stop Haloperidol

• Day 1-4: approx. 75% of initial dose
• Day 5-8: approx. 50% of initial dose
• Day 9-12: approx. 25% of initial dose
• Day 13: stop

Start Aripiprazole

• Day 1-3: start 50% of target dose
• Day 4-7: target dose

More information

• During this switch you could monitor ECG, especially in patients prone to QT-conduction problems.
• There is a possibility of QT interval prolongation.
  

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