Haloperidol LA-Zuclopenthixol LA

Start depot according to general dosing advice on the day you normally would have injected the former depot.
Testing for acceptance and possible allergic reactions in a low dose can be carried out earlier.

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During this switch you could monitor ECG, especially in patients prone to QT-conduction problems.
There is a possibility of QT interval prolongation.^[6]

↑ WHO Collaborating Centre for Drug Statistics Methodology ATC=N05AD01
↑ ^2.0 ^2.1 The Lundbeck Institute; Psychotropics; Terminal Plasma Half-lives
↑ ^3.0 ^3.1 Farmacotherapeutisch Kompas; Inleidende Tekst Antipsychotica (dutch)
↑ Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
↑ Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
↑ Stöllberger C, Huber JO, Finsterer J, Antipsychotic drugs and QT prolongation. Int Clin Psychopharmacol. 2005 Sep;20(5):243-51.

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[1] WHO Collaborating Centre for Drug Statistics Methodology ATC=N05AD01

[pts-2] 2.0 ^2.1 The Lundbeck Institute; Psychotropics; Terminal Plasma Half-lives

[ftkin-3] 3.0 ^3.1 Farmacotherapeutisch Kompas; Inleidende Tekst Antipsychotica (dutch)

[4] Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules

[5] Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.

[6] Stöllberger C, Huber JO, Finsterer J, Antipsychotic drugs and QT prolongation. Int Clin Psychopharmacol. 2005 Sep;20(5):243-51.

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Haloperidol LA-Zuclopenthixol LA

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