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Flupenthixol LA-Partial agonist

Revision as of 15:17, 20 December 2021 by Joost (talk | contribs) (Created page with "{{Drugswitch | from = Flupenthixol_LA | header= partialagonist | to = Partial agonist | stop = {{Lastinjection}} | start = {{StartArip}} | info = {{caveQT}} | view = StopDepo...")
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Flupenthixol
long acting
Type Antipsychotic
Group Thioxanthenes
links
Medscape Flupenthixol
PubChem 17012
PubMed Flupenthixol
Kompas (Dutch) Flupenthixol
Wikipedia Flupenthixol
Partial agonists

Aripiprazole
Brexpiprazole
Cariprazine

Switch medication from Flupenthixol_LA to Partial agonist.[1] [2]
Partial agonist is a collection of antipsychotic drugs having similar properties with respect to switching. A switch to member of the 'partial agonist' group from anotherdrug should be read as partial agonist-anotherdrug. Similarly, a switch from a member of the 'partial agonist' group to anotherdrug should be read as anotherdrug-partial agonist.

Nietinrijdenbord.png Stop Flupenthixol_LA
  • Day 1: Last depot injection
Eenrichtingbord.png Start Partial agonist
  • Start drug at target dose on the day you would normally have injected the next depot.
Infobord.png More information
  • During this switch you could monitor ECG, especially in patients prone to QT-conduction problems.
  • There is a possibility of QT interval prolongation.[3]
    StopDepotStartArip.jpg
Nietinrijdenbord.png — Flupenthixol_LA
Eenrichtingbord.png — Partial agonist


  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
  3. Stöllberger C, Huber JO, Finsterer J, Antipsychotic drugs and QT prolongation. Int Clin Psychopharmacol. 2005 Sep;20(5):243-51.
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