Switch medication from amitriptyline to moclobemide.[1]
[2]
Stop amitriptyline
- Day 1: Decrease with about 25% of the original dose per 3 days.
Start moclobemide
- Start with moclobemide 300 mg in 2-3 doses
- After a week the dosage of moclobemide can be increased.
More information
- No wash-out period is necessary
- ↑ Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
- ↑ Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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Stop amitriptyline 
Start moclobemide
More information