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Created page with '{{Drugswitch | from = fluvoxamine | to = agomelatine | stop = * | start = * '''Day 1-7:''' a wash-out period of one week is necessary. * '''Day 8:''' start administration o...'
{{Drugswitch
| from = fluvoxamine
| to = agomelatine
| stop =
*
| start =
* '''Day 1-7:''' a wash-out period of one week is necessary.
* '''Day 8:''' start administration of agomelatine after this period in a dosage of 25 mg/day.
* If necessary, the dosage of agomelatine can be increased to 50 mg/day.
| info =
* Fluvoxamine stops the metabolism of agomelatine via CYP1A2 (90%) and via CYP2C9/2C19 (10%).}}
| from = fluvoxamine
| to = agomelatine
| stop =
*
| start =
* '''Day 1-7:''' a wash-out period of one week is necessary.
* '''Day 8:''' start administration of agomelatine after this period in a dosage of 25 mg/day.
* If necessary, the dosage of agomelatine can be increased to 50 mg/day.
| info =
* Fluvoxamine stops the metabolism of agomelatine via CYP1A2 (90%) and via CYP2C9/2C19 (10%).}}