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Paroxetine-citalopram

343 bytes removed, 09:42, 7 May 2009
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{{Drugswitch
| from = paroxetine
| to = nortriptyline citalopram
| stop =
* '''Day 0:''' gradually Gradually reduce dosage of paroxetine to a maximum of 20 mg/day , when this dosage is > 20 mg/day. * '''Day 1:''' reduce dosage of paroxetine to When a maximum of 10 mg/day. * '''Day 8:''' reduce dosage of paroxetine to 5 20 mg/dayis reached, stop administration.
| start =
Caution * No wash-out period is necessaryneeded.* '''Day 8:''' simultaneously start administration of nortriptyline Start citalopram/escitalopram the next day in a low normal dosage of 25 20 mg/day, resp. * '''Day 15:''' stop administration of paroxetine and only continue administration of noritriptyline in a dosage of 50 10 mg/day.* "Start low, go slow" is not required, but caution is necessary!| info = * Paroxetine slows the metabolism of nortriptyline via CYP2D6. }}
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