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Created page with '{{ Drugswitch | from = venlafaxine | to = hypericum | stop = * '''Before day 0:''' gradually reduce dosage of venlafaxine to a maximum of 75 mg/day, when this dosage is > 75 ...'
{{ Drugswitch
| from = venlafaxine
| to = hypericum
| stop =
* '''Before day 0:''' gradually reduce dosage of venlafaxine to a maximum of 75 mg/day, when this dosage is > 75 mg/day.
* '''Day 1:''' reduce dosage of venlafaxine to 37,5 mg/day.
* '''Day 8:''' stop administration of venlafaxine.
| start =
* '''Day 8-14:''' a wash-out period of one week is necessary.
* '''Day 15:''' start administration of hypericum in a dosage of 300 mg three times a day (900 mg/day).
| info =
* Occurrence of serotonin syndrome is theoretically possible, so caution is necessary.
* Hypericum slows the metabolism of venlafaxine via CYP3A4. }}
| from = venlafaxine
| to = hypericum
| stop =
* '''Before day 0:''' gradually reduce dosage of venlafaxine to a maximum of 75 mg/day, when this dosage is > 75 mg/day.
* '''Day 1:''' reduce dosage of venlafaxine to 37,5 mg/day.
* '''Day 8:''' stop administration of venlafaxine.
| start =
* '''Day 8-14:''' a wash-out period of one week is necessary.
* '''Day 15:''' start administration of hypericum in a dosage of 300 mg three times a day (900 mg/day).
| info =
* Occurrence of serotonin syndrome is theoretically possible, so caution is necessary.
* Hypericum slows the metabolism of venlafaxine via CYP3A4. }}