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Created page with '{{ Drugswitch | from = mirtazapine | to = hypericum | stop = * '''Before day 0:''' gradually reduce dosage of mirtazapine to a maximum of 30 mg/day, when this dosage is > 30 ...'
{{ Drugswitch
| from = mirtazapine
| to = hypericum
| stop =
* '''Before day 0:''' gradually reduce dosage of mirtazapine to a maximum of 30 mg/day, when this dosage is > 30 mg/day.
* '''Day 1:''' reduce dosage of mirtazapine to 15 mg/day.
* '''Day 8:''' stop administration of mirtazapine.
| start =
* '''Day 8-14:''' a wash-out period of one week is necessary.
* '''Day 15:''' start administration of hypericum in a dosage of 300 mg three times a day (900 mg/day).
| info =
* Occurrence of serotonin syndrome is theoretically possible, so caution is necessary.
* Hypericum slows the metabolism of mirtazapine via CYP3A4. }}
| from = mirtazapine
| to = hypericum
| stop =
* '''Before day 0:''' gradually reduce dosage of mirtazapine to a maximum of 30 mg/day, when this dosage is > 30 mg/day.
* '''Day 1:''' reduce dosage of mirtazapine to 15 mg/day.
* '''Day 8:''' stop administration of mirtazapine.
| start =
* '''Day 8-14:''' a wash-out period of one week is necessary.
* '''Day 15:''' start administration of hypericum in a dosage of 300 mg three times a day (900 mg/day).
| info =
* Occurrence of serotonin syndrome is theoretically possible, so caution is necessary.
* Hypericum slows the metabolism of mirtazapine via CYP3A4. }}