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Tranylcypromine-trazodone

537 bytes added, 14:08, 7 May 2009
Created page with '{{Drugswitch | from = tranylcypromine | to = trazodone | stop = * Gradually decrease the dosage of tranylcypromine with 10-20 mg/week. * When a dosage of 10 mg/day is reached...'
{{Drugswitch
| from = tranylcypromine
| to = trazodone
| stop =
* Gradually decrease the dosage of tranylcypromine with 10-20 mg/week.
* When a dosage of 10 mg/day is reached, stop administration.
| start =
* '''Day 1-14:''' a wash-out period of two weeks is necessary.
* '''Day 15:''' start trazodone after this period in a dosage of 300 mg/day.
| info =
* Occurence of the serotonin syndrome is theoretically possible, so caution is necessary.
* The wash-out period is necessary for the MAO enzymes to restore their function.}}
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